Faculty Research Labs


Corr Laboratory

The research mission of the Corr Laboratory is to harness the cell's natural abilities to improve functional tissue engineering, particularly in orthopaedic soft tissues.

To attack this problem, our research is focused in three main areas: (a) Scaffold-free soft tissue engineering, (b) wound healing and biomechanics of biologic soft tissue, and (c) creating spatially-precise cellular cultures and co-cultures using laser direct writing. Current projects include...


Gilbert Laboratory

Research in the Gilbert Laboratory is focused on developing translational biomaterial approaches for spinal cord repair. There is no cure for spinal cord injury, and current approaches in clinical trials involve administration of pharmacological therapy systemically. While these pharmacological approaches may improve regeneration outcomes, they are not commonly administered directly to the lesion site. Long duration release of therapies directly to the lesion site...


Hahn Tissue Laboratory

My laboratory specializes in the development of tissue engineered replacements for small-caliber arteries and osteochondral tissues and in the regeneration of chronically scarred tissue. Our tissue regeneration strategy focuses on engineering scaffold material properties to stimulate progenitor cells to promote tissue-specific healing following implantation. This approach avoids the need for pre-implantation cell or construct culture and increases the translational...


Intes Laboratory

Biomedical imaging and instrumentation are integral to the medical diagnostic equipment and processes of today and the future.

Our laboratory goal is to develop quantitative thick-tissue optical imaging platforms for pre-clinical and clinical applications. We focus on three main areas: (a) design new optical tomographic imaging instrumentation; (b) develop new reconstruction algorithms for quantitative volumetric imaging; and (c) investigate optimal...


J. Hahn Laboratory

An effective research program in the systems area is necessarily interdisciplinary in nature. Systems engineering overlaps with applied mathematics and computer science and applications of systems engineering can be found in almost any engineering discipline as well as in physics and biology.

Our research group focuses on two general areas: One is the development of new techniques for systems analysis (e.g., sensitivity analysis, experimental design,...


Ledet Laboratory

The Musculoskeletal Mechanics Laboratory is engaged in translational research focused on orthopaedic biomechanics.

Projects include: (1) in vivo characterization of changes to the intervertebral disc and subchondral bone in the lumbar spine in response to loading; (2) Characterization of the relationship between spinal muscle fatigue or injury and increased in vivo loading of the spine; (3) Development of a novel in vivo/in vitro active/passive simulation tool...


Thompson Laboratory

Research in the Thompson Laboratory is focused on the functional repair of injuries to both the central and peripheral nervous system with an emphasis on Neuronal-Glial Interactions. Following injury intact networks need to be protected, scarring minimized, lost cells/tissue (neurons, glia, microvessel) replaced/regenerated to restore lost function. In vivo, non-neural cells (e.g. glia and neural progenitors) or implanted at the injury present site influence neuronal...


Vashishth Laboratory

Because bone's ECM and its modifications are determined by events at molecular, cellular, and tissue levels, our research spans these natural length scales in bone. Using approaches from the fields of mechanics, material science, biochemistry and cell biology we create and use experimental model systems to investigate the mechanics and biology of bone fragility associated with aging, osteoporosis and diabetes.

At the molecular level, we have identified the age...


Cell chirality on micropatterns

Wan Laboratory

The research mission of the Wan laboratory is to study physical forces in tissue development and regeneration and to develop microassays and technologies for disease diagnosis and drug screening, using integrated theoretical and experimental approaches including tissue and cell biomechanics, novel biomaterials, imaging methods, and micro/nanotechnologies.

The research program is focused on mechanics and biology at different hierarchical levels, towards...


Wang Laboratory

The Biomedical Imaging Cluster (BIC) at Rensselaer Polytechnic Institute (RPI) is a transdisciplinary team working on x-ray computed tomography, optical molecular tomography, and other unconventional methods with collaborators of unique caliber and insight. We target innovative and influential ideas and results via world-class partnerships; balance theoretical, algorithmic, systematic, and practical aspects; and train imaging “scieneers“/educators for the future. To...