Posted August 3, 2022
Deepak Vashishth has been awarded an NIH R01 grant on the topic, "Effect of Advanced Glycation Endproducts on Type 2 Diabetic and Fragility Fracture." This is a 5 year grant with a budget of $4M. The project will use in vitro biochemical models, preclinical modes of obese and non-obese T2D and human data from NIA's Health ABC study to find and establish a new biomarker of T2D fracture that captures the effects of both hyperglycemia and oxidative stress in bone. Other collaborators on the project include Jon Dordick, Dhaliwal (Upstate Medical College), Bidwell (Indiana University), and Scwartz (UCSF).